Heart disease in an otherwise healthy young athlete who is abusing anabolic steroids likely results from increased levels of low-density lipoprotein (LDL) and decreased levels of high-density lipoprotein (HDL).
Several studies suggest that anabolic steroid abuse in athletes increases LDL levels by > 20% and decreases HDL levels by 20% to 70%. These lipoprotein abnormalities have been shown to increase the risk for coronary artery disease three- to six-fold. Anabolic steroid abuse may cause cardiac ischemia by exaggerating oxygen demand at peak exercise, potentially precipitated by accelerated atherosclerosis from lipoprotein abnormalities over years of abuse.
Silver reviewed the adverse effects of anabolic steroids in a JAAOS article and reported that anabolic steroid use can lead to hypertension, changes in lipid profile, elevated liver enzymes, increased risk of tendon and muscle injury, testicular or uterine atrophy, depression, psychosis, and immunosuppression.
Achar et al. reviewed a total of 49 studies describing 1,467 athletes to investigate the cardiovascular effects of the anabolic steroid abuse. They found that anabolic steroid abuse was associated with elevated levels of LDL, low levels of HDL, elevated systolic and diastolic blood pressure, and left ventricular hypertrophy. They also noted that there were some small case studies describing fatal ventricular arrhythmias secondary to anabolic steroid abuse.
Answer 1: High density lipoprotein levels are decreased, not increased, in those abusing anabolic steroids. This decrease in HDL levels contributea to the development of heart disease in these otherwise healthy individuals.
Answer 2: Systolic and diastolic blood pressure are elevated, not decreased, after prolonged anabolic steroid use. This does not lead to heart disease in those who abuse anabolic steroids.
Answer 4: Alteration of myocardial conduction patterns (., ventricular arrhythmia) is not a cause of heart disease in anabolic steroid abusers. It is, however, a cause of sudden death in these individuals.
Answer 5: Anabolic steroids do not cause 'direct' endothelial damage to the coronary arteries.
Equipoise can produce androgenic side effects such as acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. However, the overall androgenicity of this steroid is greatly reduced due to the structural nature that creates EQ in its double bond at the carbon one and two position. Such side effects of Equipoise are still possible, but they will be strongly linked to genetic predisposition, but most will find the threshold is fairly high.
When combating the possible androgenic side effects of Equipoise, it’s important to note they are brought on by the steroid being metabolized by the 5-alpha reductase enzyme. This metabolism will reduce Boldenone to an extremely potent androgen in dihydroboldenone, far more potent than dihydrotestosterone (DHT); however, the total dihydroboldenone activity has proven to be extremely low in human beings. You will further find the androgenic nature of Boldenone will not be significantly affected by 5-alpha reductase inhibitors like Finasteride that are often used to combat the reduction to DHT.
Due to the androgenic nature of Equipoise, women may potentially experience virilization symptoms. Virilization symptoms may include body hair growth, a deepening of the vocal chords and clitoral enlargement. However, the low androgenicity will make this steroid possible to use for some women without such symptoms. At the same time, the extremely slow acting nature of the compound can make it difficult to control regarding blood levels, and alternative steroids may be preferred. Without question, individual sensitivity will dictate a lot. If Equipoise is used and virilization symptoms begin to show, use should be discontinued immediately at their onset and they will fade away. If symptoms begin to show and are ignored, the symptoms may become irreversible.
The most commonly used AAS in medicine are testosterone and its various esters (but most commonly testosterone undecanoate , testosterone enanthate , testosterone cypionate , and testosterone propionate ),  nandrolone esters (most commonly nandrolone decanoate and nandrolone phenylpropionate ), stanozolol , and metandienone (methandrostenolone).  Others also available and used commonly but to a lesser extent include methyltestosterone , oxandrolone , mesterolone , and oxymetholone , as well as drostanolone propionate , metenolone (methylandrostenolone), and fluoxymesterone .  Dihydrotestosterone (DHT; androstanolone, stanolone) and its esters are also notable, although they are not widely used in medicine.  Boldenone undecylenate and trenbolone acetate are used in veterinary medicine .