It needs to be taken for 4-8 weeks. Its half-life is generally referred to in the range of 2 to 3 days. It is applied every other or every third day. Most practical and most logical is to apply it every other day. It is usually used during the whole cycle, or in the second half, when it serves as dihydrotestosterone. For the purpose of improving the figure and increasing the performance, dosage of Drostanolone is usually in the range 200-400 mg per week. After taking the substance, it can be detected in the body for 6-8 weeks.
Within bodybuilding, weight lifting and other sports communities, the use of Drostanolone propionate is valued for its assistance in building harder muscle mass and increasing overall muscle density. As a result, the androgenic steroid is particularly desirable among individuals looking to improve their overall muscular strength without “bulking up” excessively or increasing muscle mass. In addition, the use of Drostanolone propionate is popular among bodybuilding enthusiasts, as regular use of the steroid can create a more chiseled physique by helping to build denser musculature.
Tibolone has tissue -selective estrogenic effects, with desirable effects in bone , the brain , and the vagina , and lack of undesirable action in the endometrium and breasts .  Its tissue selectivity is the result of metabolism , enzyme modulation (., of estrogen sulfatase and estrogen sulfotransferase ), and receptor modulation that vary in different target tissues, and differs mechanistically from that of selective estrogen receptor modulators (SERMs) such as tamoxifen , which produce their tissue-selectivity via means of modulation of the ER.   As such, to distinguish it from SERMs, tibolone has been described as a "selective tissue estrogenic activity regulator" (STEAR),  and also as a "selective estrogen enzyme modulator" (SEEM).